NEUROD2 Antikörper (AA 121-250) (AbBy Fluor® 647)

Produktnummer ABIN1394094

This anti-NEUROD2 antibody (ABIN1394094) is a Rabbit Polyclonal antibody detecting NEUROD2 in WB, IF (cc), IF (p). Suitable for Human.

Quick Overview for NEUROD2 Antikörper (AA 121-250) (AbBy Fluor® 647) (ABIN1394094)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEUROD2 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-NEUROD2 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 121-250

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neuro D2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Andere Bezeichnung: Neuro D2

Hintergrund:

Synonyms: bHLHa1, Class A basic helix-loop-helix protein 1, class A basic helix loop helix protein 1, NDF2_HUMAN, NDR2, NDRF, Neuro-D2, NeuroD-related factor, NeuroD2, Neurogenic dferentiation factor 2, NDF2_HUMAN, neuroD related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic dferentiation 2, Neurogenic dferentiation factor 2, neuronal dferentiation 2.

Background: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.