NGRN Antikörper (AA 96-200) (FITC)

Produktnummer ABIN1394084

Produktdetails anti-NGRN Antikörper (FITC)

Target: NGRN (Neugrin, Neurite Outgrowth Associated (NGRN))

Bindungsspezifität: AA 96-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NGRN Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neugrin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NGRN

Target: NGRN (Neugrin, Neurite Outgrowth Associated (NGRN))

Andere Bezeichnung: Neugrin (NGRN Produkte)

Hintergrund:

Synonyms: DSC92, FI58Gm, Mesenchymal stem cell protein DSC92, Neugrin, Neugrin neurite outgrowth associated, Neurite outgrowth associated protein, Neurite outgrowth-associated protein, Ngrn, NGRN_HUMAN, Spinal cord-derived protein FI58G.

Background: Neugrin, also known as NGRN, mesenchymal stem cell protein DSC92, neurite outgrowth-associated protein or spinal cord-derived protein FI58G, is a 291 amino acid protein that plays a role in neuronal differentiation and belongs to the neugrin family. As both a secreted and nuclear protein, neugrin exists as two alternatively spliced isoforms and is highly expressed in skeletal muscle, brain and heart. Neugrin is upregulated in neuroblastostoma cells by retinoic acid treatment and is encoded by a gene that maps to human chromosome 15q26.1. Chromosome 15 houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.