ACBD3 Antikörper (AA 65-160) (FITC)

Produktnummer ABIN1394054

Der Kaninchen Polyklonal Anti-ACBD3-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, ACBD3 in Proben von Human zu detektieren.

Kurzübersicht für ACBD3 Antikörper (AA 65-160) (FITC) (ABIN1394054)

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACBD3 Antikörper ist konjugiert mit FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ACBD3 Antikörper (FITC)

Bindungsspezifität: AA 65-160

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ACBD3

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Andere Bezeichnung: ACBD3

Hintergrund:

Synonyms: ACBD 3, ACBD3, Acyl CoA binding domain containing protein 3, Acyl Coenzyme A binding domain containing 3, Acyl-CoA-binding domain-containing protein 3, GCP 60, GCP60, GCP60_HUMAN, GOCAP 1, GOCAP1, Golgi complex associated protein 1 60 kDa, Golgi complex associated protein 1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, GOLPH 1, GOLPH1, PAP 7, PAP7, PBR and PKA associated protein 7, PBR associated protein, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor associated protein PAP7, Peripheral benzodiazepine receptor-associated protein PAP7, Peripherial benzodiazepine receptor associated protein, PKA RIalpha associated protein.

Background: ACBD3 (acyl-CoA-binding domain-containing protein 3), also known as GCP60 (Golgi resident protein GCP60), GOCAP1, PAP7 or GOLPH1, is a Golgi apparatus membrane protein that contains one ACB (acyl-CoA-binding) domain and one GOLD (Golgi dynamics) domain which is essential for its interaction with other proteins. Expressed ubiquitously with highest expression in ovary and testis, ACBD3 is responsible for maintaining Golgi structure and, through binding to Giantin (golgin subfamily B member 1), functions to mediate protein transport between the Golgi and the endoplasmic reticulum (ER). Changes in the subcellular location of ACBD3 trigger signaling cascades within the Golgi that regulate cell fate and cell cycle progression. Additionally, ACBD3 is thought to act as a peripheral-type benzodiazepine receptor-associated protein, possibly playing a role in hormonal regulation and steroid formation.