NELL2 Antikörper (AA 201-300) (AbBy Fluor® 555)

Produktnummer ABIN1393961

Der Kaninchen Polyklonal Anti-NELL2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, NELL2 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für NELL2 Antikörper (AA 201-300) (AbBy Fluor® 555) (ABIN1393961)

Target: NELL2 (NEL-Like 2 (Chicken) (NELL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NELL2 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-NELL2 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NELL2/NRP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NELL2

Target: NELL2 (NEL-Like 2 (Chicken) (NELL2))

Andere Bezeichnung: NELL2/NRP2

Hintergrund:

Synonyms: A330108N19Rik, Mel91, MEL91 protein, NEL like 2 chicken, NEL-like protein 2, Nel-related protein 2, NELL2, NELL2_HUMAN, NRP2, Protein kinase C-binding protein NELL2, R75516.

Background: NELL2 is a secreted glycoprotein with one N-terminal TSP-like domain, five VWFC (von Willebrand factor C) domains and six EGF-like repeats that participate in calcium binding. NELL2 exists as a homotrimer associated with the endoplasmic reticulum (ER) and is specifically expressed in neurons playing a role in calcium-dependent intracellular events. NELL2 may act as a trophic factor in addition to its role as a signaling molecule implicated in the regulation of cell growth and differentiation. Due to alternative splicing, an additional NELL2 isoform exists that is identical to full length NELL2 except that it lacks the signal peptide that directs secretion. The additional isoform is therefore retained in the cytosol and functions as a non-secreted cytoplasmic protein that interacts with PKC bI.