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NERP-1 Antikörper (AA 231-330) (FITC)

NERP-1 Reaktivität: Maus, Ratte, Zebrafisch (Danio rerio) WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1393370
  • Target Alle NERP-1 Antikörper anzeigen
    NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))
    Bindungsspezifität
    • 14
    • 11
    • 7
    AA 231-330
    Reaktivität
    • 15
    • 14
    • 14
    • 11
    Maus, Ratte, Zebrafisch (Danio rerio)
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NERP-1 Antikörper ist konjugiert mit FITC
    Applikation
    • 15
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte, Zebrafisch (Danio rerio)
    Homologie
    Human,Cow,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NERP1
    Isotyp
    IgG
    Top Product
    Discover our top product NERP-1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NERP-1 (Neuroendocrine Regulatory Peptide 1 (NERP-1))
    Andere Bezeichnung
    VGF/NERP-1 (NERP-1 Produkte)
    Synonyme
    Gm1052 antikoerper, VGF nerve growth factor inducible antikoerper, VGF antikoerper, Vgf antikoerper
    Hintergrund

    Synonyms: Nerve growth factor inducible, Neurosecretory protein VGF, VGF, VGF_HUMAN, SCG7, SgVII, Neuroendocrine regulatory peptide-1, NERP-1, NERP1

    Background: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

    Gen-ID
    7425
    UniProt
    O15240
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