SPG21 Antikörper (AA 151-250) (AbBy Fluor® 555)

Produktnummer ABIN1393307

Der Kaninchen Polyklonal Anti-SPG21-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, SPG21 in Proben von Human zu detektieren.

Kurzübersicht für SPG21 Antikörper (AA 151-250) (AbBy Fluor® 555) (ABIN1393307)

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG21 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SPG21 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPG21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPG21

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Andere Bezeichnung: SPG21

Hintergrund:

Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.

Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.