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Receptor Accessory Protein 1 Antikörper (AA 53-150) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Receptor Accessory Protein 1 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN1393117

Kurzübersicht für Receptor Accessory Protein 1 Antikörper (AA 53-150) (Biotin) (ABIN1393117)

Target

Alle Receptor Accessory Protein 1 (REEP1) Antikörper anzeigen
Receptor Accessory Protein 1 (REEP1)

Reaktivität

  • 23
  • 12
  • 8
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Maus

Wirt

  • 26
  • 2
Kaninchen

Klonalität

  • 26
  • 2
Polyklonal

Konjugat

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Receptor Accessory Protein 1 Antikörper ist konjugiert mit Biotin

Applikation

  • 28
  • 13
  • 13
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 53-150

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human REEP1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    Receptor Accessory Protein 1 (REEP1)

    Andere Bezeichnung

    REEP1

    Hintergrund

    Synonyms: C2orf23, Chromosome 2 open reading frame 23, FLJ13110, Receptor accessory protein 1, Receptor expression-enhancing protein 1, Reep1, REEP1_HUMAN, SPG31.

    Background: Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.

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