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PQBP1 Antikörper (AA 185-265) (Biotin)

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch PQBP1 in WB, ELISA, IHC (p), IHC (fro). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1393111

Kurzübersicht für PQBP1 Antikörper (AA 185-265) (Biotin) (ABIN1393111)

Target

Alle PQBP1 Antikörper anzeigen
PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Reaktivität

  • 36
  • 9
  • 7
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
Human

Wirt

  • 34
  • 3
Kaninchen

Klonalität

  • 34
  • 3
Polyklonal

Konjugat

  • 20
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PQBP1 Antikörper ist konjugiert mit Biotin

Applikation

  • 30
  • 13
  • 13
  • 12
  • 9
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 185-265

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PQBP1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

    Andere Bezeichnung

    PQBP1

    Hintergrund

    Synonyms: 38 kDa nuclear protein containing a WW domain, Mental retardation, X linked 55, MRX55, MRXS3, MRXS8, Npw38, Nuclear protein containing WW domain 38 kD, Polyglutamine binding protein 1, Polyglutamine tract binding protein 1, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP 1, PQBP-1, PQBP1, PQBP1_HUMAN, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome.

    Background: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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