Tppp Antikörper (AA 61-150) (AbBy Fluor® 647)

Produktnummer ABIN1392666

Dieses Anti-Tppp-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Tppp in WB, IF (cc) und IF (p). Geeignet für Maus.

Kurzübersicht für Tppp Antikörper (AA 61-150) (AbBy Fluor® 647) (ABIN1392666)

Target: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tppp Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Tppp Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 61-150

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPPP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Tppp

Target: Tppp (Tubulin Polymerization Promoting Protein (Tppp))

Andere Bezeichnung: TPPP

Hintergrund:

Synonyms: Tubulin Polymerization Promoting Protein 24, 25 kDa brain specic protein, 25 kDa brain-specic protein, Brain specic protein p25 alpha, Glycogen synthase kinase 3 GSK3 inhibitor p24, p24, p25, p25-alpha, p25alpha, TPPP, TPPP/p25, TPPP_HUMAN, TPPP1, Tubulin polymerization promoting protein, Tubulin polymerization-promoting protein.

Background: Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport. TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm. TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks. TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope. TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome.