COQ10B Antikörper (AA 38-110) (Biotin)

Produktnummer ABIN1392565

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COQ10B in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für COQ10B Antikörper (AA 38-110) (Biotin) (ABIN1392565)

Target: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ10B Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-COQ10B Antikörper (Biotin)

Bindungsspezifität: AA 38-110

Spezifität: Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COQ10B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu COQ10B

Target: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Andere Bezeichnung: COQ10B

Hintergrund:

Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

Background: COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

Gen-ID: 80219

UniProt: Q9H8M1