FOXG1 Antikörper (AbBy Fluor® 488)

Produktnummer ABIN1391974

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXG1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für FOXG1 Antikörper (AbBy Fluor® 488) (ABIN1391974)

Target: FOXG1 (Forkhead Box G1 (FOXG1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXG1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB)

Produktdetails anti-FOXG1 Antikörper (AbBy Fluor® 488)

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXG1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FOXG1

Target: FOXG1 (Forkhead Box G1 (FOXG1))

Andere Bezeichnung: Foxg1/Bf-1

Hintergrund:

Synonyms: BF 1, BF 2, BF-1, BF-2, BF1, BF2 , Brain factor 1, Brain factor 2, FHKL, FKH2, FKHL1, FKHL2, FKHL2, FKHL3, FKHL4, Forkhead box G1A, Forkhead box G1B, Forkhead box protein G1, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead drosophila homolog like 2, Forkhead like 1, Forkhead like 2, FOXG1_HUMAN.

Background: The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (14). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1).