ENTPD2 Antikörper (AA 401-495) (FITC)

Produktnummer ABIN1391726

Der Kaninchen Polyklonal Anti-ENTPD2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, ENTPD2 in Proben von Ratte zu detektieren.

Kurzübersicht für ENTPD2 Antikörper (AA 401-495) (FITC) (ABIN1391726)

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENTPD2 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ENTPD2 Antikörper (FITC)

Bindungsspezifität: AA 401-495

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ENTPD2

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Andere Bezeichnung: ENTPD2/CD39L1

Hintergrund:

Synonyms: CD39 antigen like 1, CD39 antigen-like 1, CD39 like1, CD39L1, CD39like1, ecto ATP diphosphohydrolase 2, ecto ATPase 2, ecto ATPDase 2, Ecto-ATP diphosphohydrolase 2, Ecto-ATPase 2, Ecto-ATPDase 2, ectoATPase 2, ectoATPDase 2, Ectonucleoside triphosphate diphosphohydrolase 2, ENTP2_HUMAN, Entpd2, NTPDase 2, NTPDase2.

Background: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.