SLK Antikörper (AA 885-931) (AbBy Fluor® 555)

Produktnummer ABIN1391543

Der Kaninchen Polyklonal Anti-SLK-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, SLK in Proben von Human zu detektieren.

Kurzübersicht für SLK Antikörper (AA 885-931) (AbBy Fluor® 555) (ABIN1391543)

Target: SLK (STE20-Like Kinase (SLK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLK Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SLK Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 885-931

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SLK

Target: SLK (STE20-Like Kinase (SLK))

Andere Bezeichnung: STK2

Hintergrund:

Synonyms: CTCL tumor antigen se20 9, LOSK, se20 9, Serine/threonine protein kinase 2, STK2, SLK, SNF1 sucrose nonfermenting like kinase, STE20 like serine/threonine-protein kinase, STE20 related kinase, STK2, SLK_HUMAN.

Background: SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

UniProt: Q9H2G2