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DCLK1 Antikörper (AA 151-250) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DCLK1 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1391377

Kurzübersicht für DCLK1 Antikörper (AA 151-250) (Biotin) (ABIN1391377)

Target

Alle DCLK1 Antikörper anzeigen
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

Reaktivität

  • 95
  • 43
  • 14
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 81
  • 16
  • 1
Kaninchen

Klonalität

  • 65
  • 33
Polyklonal

Konjugat

  • 55
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DCLK1 Antikörper ist konjugiert mit Biotin

Applikation

  • 75
  • 32
  • 31
  • 24
  • 15
  • 13
  • 13
  • 12
  • 9
  • 8
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 151-250

    Homologie

    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DCAMKL1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    Andere Bezeichnung

    DCAMKL1

    Hintergrund

    Synonyms: Calcium/calmodulin-dependent protein kinase type I-like CPG16, Cpg16, Dcl, Dclk, Dclk1, DCLK1_HUMAN, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, KIAA0369, Serine/threonine-protein kinase DCAMKL1, Serine/threonine-protein kinase DCLK1.

    Background: Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity.

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