Syntaxin 12 Antikörper (AA 101-200) (FITC)

Produktnummer ABIN1390922

Der Kaninchen Polyklonal Anti-Syntaxin 12-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Syntaxin 12 in Proben von Maus zu detektieren.

Kurzübersicht für Syntaxin 12 Antikörper (AA 101-200) (FITC) (ABIN1390922)

Target: Syntaxin 12 (STX12)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 12 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Syntaxin 12 Antikörper (FITC)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Syntaxin 13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Syntaxin 12

Target: Syntaxin 12 (STX12)

Andere Bezeichnung: Syntaxin 13

Hintergrund:

Synonyms: Syntaxin13, Syntaxin 13, Syntaxin-13, Syx13, Syx 13, Syx-13, CG11278, CT31479, Dm Syx13, ff16, l301470, STX12_RAT.

Background: Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.

Gen-ID: 65033

Pathways: Synaptic Vesicle Exocytosis