SV2C Antikörper (AA 451-550) (AbBy Fluor® 555)

Produktnummer ABIN1390847

Der Kaninchen Polyklonal Anti-SV2C-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, SV2C in Proben von Human zu detektieren.

Kurzübersicht für SV2C Antikörper (AA 451-550) (AbBy Fluor® 555) (ABIN1390847)

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SV2C Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SV2C Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 451-550

Homologie: Human,Mouse,Rat,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SV2C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SV2C

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Andere Bezeichnung: SV2C

Hintergrund:

Synonyms: Synaptic vesicle protein 2c, SV2C_HUMAN.

Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

Gen-ID: 22987