NOVA1 Antikörper (AA 411-510) (AbBy Fluor® 555)

Produktnummer ABIN1390595

Der Kaninchen Polyklonal Anti-NOVA1-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, NOVA1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für NOVA1 Antikörper (AA 411-510) (AbBy Fluor® 555) (ABIN1390595)

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOVA1 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-NOVA1 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 411-510

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOVA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NOVA1

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Andere Bezeichnung: Nova1

Hintergrund:

Synonyms: Neuro oncological ventral antigen 1, Neuro-oncological ventral antigen 1, NOVA 1, Nova-1, Nova1, NOVA1_HUMAN, Onconeural ventral antigen 1, Paraneoplastic Ri antigen, RNA binding protein Nova 1, RNA-binding protein Nova-1, Ventral neuron specic protein 1, Ventral neuron-specic protein 1.

Background: Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).

UniProt: P51513