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ISL2 Antikörper (AA 201-300) (Biotin)

This anti-ISL2 antibody (ABIN1390579) is a Rabbit Polyclonal antibody detecting ISL2 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN1390579

Kurzübersicht für ISL2 Antikörper (AA 201-300) (Biotin) (ABIN1390579)

Target

Alle ISL2 Antikörper anzeigen
ISL2 (ISL LIM Homeobox 2 (ISL2))

Reaktivität

  • 53
  • 20
  • 18
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 46
  • 7
Kaninchen

Klonalität

  • 48
  • 5
Polyklonal

Konjugat

  • 28
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ISL2 Antikörper ist konjugiert mit Biotin

Applikation

  • 44
  • 18
  • 13
  • 13
  • 9
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Islet 2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    ISL2 (ISL LIM Homeobox 2 (ISL2))

    Andere Bezeichnung

    Islet 2

    Hintergrund

    Synonyms: Insulin gene enhancer protein ISL 2, Insulin gene enhancer protein ISL-2, Insulin gene enhancer protein ISL2, ISL 2, ISL 2 transcription factor, ISL 2 transcription factor LIM/homeodomain, ISL2, ISL2 transcription factor, ISL2 transcription factor LIM/homeodomain, ISL2_HUMAN, Islet-2, Islet2, FLJ10160.

    Background: Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2. Islet-2 is a nuclear protein that contains two N-terminal LIM domains, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus. Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways. Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates. Somatic, but not visceral, motor neurons maintain Islet-2 expression at later embryonic stages. An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character. Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character.

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