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Endothelin 2 Antikörper (AA 49-59) (AbBy Fluor® 350)

This anti-Endothelin 2 antibody (ABIN1390329) is a Rabbit Polyclonal antibody detecting Endothelin 2 in IF (cc), IF (p). Suitable for Cat.
Produktnummer ABIN1390329

Kurzübersicht für Endothelin 2 Antikörper (AA 49-59) (AbBy Fluor® 350) (ABIN1390329)

Target

Alle Endothelin 2 (EDN2) Antikörper anzeigen
Endothelin 2 (EDN2)

Reaktivität

  • 40
  • 14
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Cat

Wirt

  • 51
  • 5
Kaninchen

Klonalität

  • 52
  • 4
Polyklonal

Konjugat

  • 26
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endothelin 2 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation

  • 25
  • 15
  • 13
  • 12
  • 12
  • 10
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    AA 49-59

    Kreuzreaktivität

    Cat

    Homologie

    Human,Mouse,Rat,Dog,Cow,Cat,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Endolin 2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Endothelin 2 (EDN2)

    Andere Bezeichnung

    ET-2/Endothelin 2

    Hintergrund

    Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.

    Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).

    Pathways

    Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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