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CCT2 Antikörper (AA 131-230) (Biotin)

This anti-CCT2 antibody (ABIN1390255) is a Rabbit Polyclonal antibody detecting CCT2 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse.
Produktnummer ABIN1390255

Kurzübersicht für CCT2 Antikörper (AA 131-230) (Biotin) (ABIN1390255)

Target

Alle CCT2 Antikörper anzeigen
CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Reaktivität

  • 69
  • 43
  • 25
  • 8
  • 8
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 53
  • 17
  • 1
Kaninchen

Klonalität

  • 49
  • 22
Polyklonal

Konjugat

  • 45
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCT2 Antikörper ist konjugiert mit Biotin

Applikation

  • 57
  • 24
  • 20
  • 17
  • 13
  • 13
  • 9
  • 8
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CCT2/TCP1 beta

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

    Andere Bezeichnung

    CCT2/TCP1 beta

    Hintergrund

    Synonyms: CCT 2, CCT beta, CCT-beta, CCT-2, CCTB, Chaperonin containing t complex polypeptide 1 beta subunit, Chaperonin containing t complex polypeptide 1 subunit 2, Chaperonin containing TCP1 subunit 2, Chaperonin containing TCP1 subunit 2 beta, CTP:phosphocholine cytidylyltransferase 2, MGC142074, MGC142076, MGC94480, PRO1633, T complex protein 1 beta subunit, T complex protein 1 subunit beta, T-complex protein 1 subunit beta, TCP 1 beta, TCP-1-beta, TCPB_HUMAN, 99D8.1.

    Background: CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15 % of newly synthesized eukaryotic proteins (2). CCT2 is the _-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5), CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.

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