TMED10 Antikörper (AA 101-200) (FITC)

Produktnummer ABIN1390232

Der Kaninchen Polyklonal Anti-TMED10-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, TMED10 in Proben von Human und Maus zu detektieren.

Kurzübersicht für TMED10 Antikörper (AA 101-200) (FITC) (ABIN1390232)

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMED10 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TMED10 Antikörper (FITC)

Bindungsspezifität: AA 101-200

Spezifität: KO-Validated

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMP21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TMED10

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Andere Bezeichnung: TMP21

Hintergrund:

Synonyms: p23, p24 family protein delta 1, p24delta, p24delta1, S31I125, S31III125, TMED 10, TMED10, Tmp 21 I, Tmp 21, Tmp 21 I, Transmembrane emp24 domain containing protein 10, Transmembrane emp24-like trafficking protein 10 yeast, Transmembrane protein Tmp21, Transmembrane trafficking protein 21kD, 1110014C03Rik, 21 kDa transmembrane trafficking protein, MGC102351, TMEDA_HUMAN.

Background: MP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.