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GRAF Antikörper (AA 1-100) (FITC)

ARHGAP26 Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1390154
  • Target Alle GRAF (ARHGAP26) Antikörper anzeigen
    GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 36
    • 3
    • 1
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRAF Antikörper ist konjugiert mit FITC
    Applikation
    • 33
    • 21
    • 18
    • 12
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GRAF1
    Isotyp
    IgG
    Top Product
    Discover our top product ARHGAP26 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
    Andere Bezeichnung
    GRAF1 (ARHGAP26 Produkte)
    Synonyme
    ARHGAP26 antikoerper, GRAF antikoerper, GRAF1 antikoerper, OPHN1L antikoerper, OPHN1L1 antikoerper, 1810044B20Rik antikoerper, 2610010G17Rik antikoerper, 4933432P15Rik antikoerper, AI853435 antikoerper, mKIAA0621 antikoerper, Rho GTPase activating protein 26 antikoerper, ARHGAP26 antikoerper, Arhgap26 antikoerper
    Hintergrund

    Synonyms: arhgap 26, ARHGAP26, FLJ42530, GRAF, GRAF1, GTPase regulator associated with focal adhesion kinase, GTPase regulator associated with focal adhesion kinase pp125FAK, KIAA0621, oligophrenin 1 like protein, Oligophrenin-1-like protein, oligophrenin1like protein, OPHN1L, OPHN1L1, RHG26_HUMAN, Rho GTPase activating protein 26, Rho GTPase activating protein26, Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26.

    Background: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

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