GRK4/GRK5/GRK6 (AA 181-280) Antikörper (AbBy Fluor® 555)

Produktnummer ABIN1390073

Der Kaninchen Polyklonal Anti--Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für GRK4/GRK5/GRK6 (AA 181-280) Antikörper (AbBy Fluor® 555) (ABIN1390073)

Target: GRK4/GRK5/GRK6

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: AA 181-280

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRK6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: GRK4/GRK5/GRK6

Andere Bezeichnung: GRK4, GRK5, GRK6

Hintergrund:

Synonyms: GRK4: G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4, GPRK2L, GPRK4 GRK5: G protein-coupled receptor kinase 5, G protein-coupled receptor kinase GRK5, GPRK5 GRK6: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.

Gen-ID: 2868, 2869, 2870