H13 Antikörper (AA 251-350) (AbBy Fluor® 350)

Produktnummer ABIN1389735

Dieses Anti-H13-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von H13 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für H13 Antikörper (AA 251-350) (AbBy Fluor® 350) (ABIN1389735)

Target: H13 (Histocompatibility 13 (H13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H13 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-H13 Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 251-350

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Signal Peptide Peptidase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu H13

Target: H13 (Histocompatibility 13 (H13))

Andere Bezeichnung: Spp/Signal Peptide Peptidase

Hintergrund:

Synonyms: Histocompatibility minor 13, HM 13, HM13, HM13_HUMAN, IMP 1, IMP-1, IMP1, IMPAS, IMPAS-1, Intramembrane Protease 1, Intramembrane protease, Minor Histocompatibility 13, Minor histocompatibility antigen 13, Minor histocompatibility antigen H13, MSTP086, Presenilin like protein 3, Presenilin-like protein 3, PSENL 3, PSENL3, PSL 3, PSL3, Signal peptide peptidase, Signal peptide peptidase beta, SPP, dJ324O17.1, H13, hIMP1, hIMP1 protein.

Background: The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.

Gen-ID: 207