Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 161-260) Antikörper (Biotin)

Produktnummer ABIN1388863

Produktdetails

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Bindungsspezifität: AA 161-260

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STAU2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Andere Bezeichnung: STAU2 (STAU2 Produkte)

Synonyme: r-staufen protein antikoerper, staufen (RNA binding protein) homolog 2 (Drosophila) antikoerper, staufen double-stranded RNA binding protein 2 antikoerper, Stau2 antikoerper

Hintergrund:

Synonyms: Double stranded RNA binding protein Staufen homolog 2, MGC119606, STAU 2, STAU2, STAU-2, Staufen Drosophila, RNA-binding protein homolog 2, Staufen homolog 2, Staufen RNA binding protein homolog 2, Staufen, RNA binding protein, homolog 2 Drosophila, 39K2, 39K3, DKFZp781K0371, STAU2_HUMAN.

Background: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5 % and 59.9 % similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.