GluR1, GluR2 Antikörper (AA 141-240) (Biotin)

Produktnummer ABIN1388335

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GluR1, GluR2 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für GluR1, GluR2 Antikörper (AA 141-240) (Biotin) (ABIN1388335)

Target: GluR1, GluR2 (GRIA1/2) (Glutamate Receptor, Ionotropic, AMPA 1/2 (GRIA1/2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GluR1, GluR2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GluR1, GluR2 Antikörper (Biotin)

Bindungsspezifität: AA 141-240

Spezifität: Due to the similarity of this protein to GluR2, there is a chance that this antibody will react with this protein based on homology.

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GluR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GluR1, GluR2

Target: GluR1, GluR2 (GRIA1/2) (Glutamate Receptor, Ionotropic, AMPA 1/2 (GRIA1/2))

Andere Bezeichnung: GluR1, GluR2

Hintergrund:

Synonyms: GLUH1, GLUR1, GLURA, GluA1, HBGR1, Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GRIA1

Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gen-ID: 2890

UniProt: P42261