LGALS12 Antikörper (AA 101-200)

Produktnummer ABIN1388015

Der Kaninchen Polyklonal anti-LGALS12 Antikörper wird verwendet zum Nachweis von LGALS12 in Proben von Human. Er wurde validiert für WB, FACS, IF (cc), IF (p), IHC (fro) und IHC (p).

Kurzübersicht für LGALS12 Antikörper (AA 101-200) (ABIN1388015)

Target: LGALS12 (Lectin, Galactoside-Binding, Soluble, 12 (LGALS12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGALS12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LGALS12 Antikörper

Bindungsspezifität: AA 101-200

Verwendungszweck: Galectin 12 Polyclonal Antibody

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Galectin 12/LGALS12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LGALS12

Target: LGALS12 (Lectin, Galactoside-Binding, Soluble, 12 (LGALS12))

Andere Bezeichnung: Galectin 12

Hintergrund:

Synonyms: Galectin related inhibitor of proliferation, galectin-12, GRIP1, Lectin galactoside binding soluble 12 galectin 12, LEG12_HUMAN.

Background: Galectin-12, also designated galectin-related inhibitor of proliferation 1 in mouse, is a 314 amino acid protein encoded by the human gene LGALS12. Galectin-12 is a member of the galectin family consisting of b-galactoside-binding proteins with conserved carbohydrate recognition domains. Galectin-12 binds lactose and may participate in the apoptosis of adipocytes. This protein is preferentially expressed in peripheral blood leukocytes and adipocytes. Galectin-12 is induced by cell cycle block at the G1 phase and causes G1 arrest when overexpressed. The galectin-12 gene is expressed in mouse preadipo-cytes and is upregulated when preadipocytes undergo cell cycle arrest, concomitant with acquisition of the competence to undergo differentiation in response to adipogenic hormone stimulation. Galectin-12 is an adipocyte-expressed protein which is downregulated by various insulin resistance-inducing hormones. As a result, galectin-12 may play a role in the pathogenesis of insulin resistance.

Gen-ID: 85329