DHRS7 Antikörper (AA 61-160)

Produktnummer ABIN1387988

Produktdetails anti-DHRS7 Antikörper

Target: DHRS7 (Dehydrogenase/reductase (SDR Family) Member 7 (DHRS7))

Bindungsspezifität: AA 61-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHRS7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHRS7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DHRS7

Target: DHRS7 (Dehydrogenase/reductase (SDR Family) Member 7 (DHRS7))

Andere Bezeichnung: Dhrs7 (DHRS7 Produkte)

Synonyme: DR-NR3 antikoerper, MGC80755 antikoerper, MGC107821 antikoerper, MGC197379 antikoerper, MGC197409 antikoerper, zgc:154087 antikoerper, SDR34C1 antikoerper, retDSR4 antikoerper, retSDR4 antikoerper, 2310016E22Rik antikoerper, 5730564L20Rik antikoerper, AW061210 antikoerper, Retdsr4 antikoerper, Retsdr4 antikoerper, dehydrogenase/reductase (SDR family) member 7-like 1 antikoerper, dehydrogenase/reductase 7 antikoerper, dehydrogenase/reductase (SDR family) member 7 L homeolog antikoerper, dehydrogenase/reductase (SDR family) member 7 antikoerper, Dhrs7l1 antikoerper, DHRS7 antikoerper, dhrs7.L antikoerper, dhrs7 antikoerper, Dhrs7 antikoerper

Hintergrund:

Synonyms: CGI 86, CGI86, Dehydrogenase/reductase SDR family member 7, DHRS7A, retDSR4, Retinal short chain dehydrogenase/reductase 4, RETSDR4, DHRS7_HUMAN.

Background: DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Gen-ID: 51635