Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (AA 10-60) Antikörper

Produktnummer ABIN1387969

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in IHC (p) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Hemoglobin Alpha 1 + 2 (HBA1,HBA2) (AA 10-60) Antikörper (ABIN1387969)

Target: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: AA 10-60

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Hemoglobin alpha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Hemoglobin Alpha 1 + 2 (HBA1,HBA2)

Andere Bezeichnung: HBA1+HBA2

Hintergrund:

Synonyms: HBH, HBA-T3, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008].

Gen-ID: 3039

UniProt: P69905