LHX4 Antikörper (AA 171-280)

Produktnummer ABIN1387875

Produktdetails anti-LHX4 Antikörper

Target: LHX4 (LIM Homeobox 4 (LHX4))

Bindungsspezifität: AA 171-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LHX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lhx4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LHX4

Target: LHX4 (LIM Homeobox 4 (LHX4))

Andere Bezeichnung: Lhx4 (LHX4 Produkte)

Synonyme: LHX4 antikoerper, si:dkeyp-35f11.3 antikoerper, CPHD4 antikoerper, A330062J17Rik antikoerper, Gsh-4 antikoerper, Gsh4 antikoerper, LIM homeobox 4 antikoerper, LIM homeobox protein 4 antikoerper, LHX4 antikoerper, lhx4 antikoerper, Lhx4 antikoerper

Hintergrund:

Synonyms: Gsh 4, Gsh4, Lhx4, LHX4_HUMAN, LIM Homeobox 4, LIM homeobox protein 4, LIM/homeobox protein Lhx4.

Background: The LIM domain (a zinc finger structure) is a protein-protein interaction motif found in several protein types, including homeodomain transcription factors and kinases, which has a role in many cellular processes. The LIM family of homeodomain proteins plays a role in organismal differentiation and development. Specifically, LHX4 and closely related LHX3 play essential roles in multiple developmental stages of the pituitary gland in mice. The LHX4 gene is expressed in murine fetal brain, spinal cord and cerebral cortex. In addition, LHX4 is expressed in the cerebral cortex and in the motor neurons of the CNS in adult rodents. A specific murine LHX4 gene mutation results in a short stature phenotype, pituitary and cerebelllar defects and sella turcica malformations. The LHX4 gene may be implicated in the t(1,4)(q25,q32) chromosomal translocation, which is associated with acute lymphoblastic leukemia. The LHX4 gene is also expressed in leukemic cells and may activate leukemogenesis. The human LHX4 gene maps to chromosome 1q25 and encodes a 390 amino acid protein.