FADS2 Antikörper

Produktnummer ABIN1387859

Der Kaninchen Polyklonal Anti-FADS2-Antikörper wurde für WB validiert. Er ist geeignet, FADS2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für FADS2 Antikörper (ABIN1387859)

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FADS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FADS2 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FADS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FADS2

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Andere Bezeichnung: Fads2

Hintergrund:

Synonyms: D6D, Delta6 desaturase, Delta6 fatty acid desaturase, DES 6, DES6, FADS 2, FADSD 6, FADSD6, Fatty acid desaturase 2, linoleoyl-CoA desaturase delta-6-desaturase like 2, LLCDL 2, LLCDL2, SLL0262, TU 13, TU13, FADS2_HUMAN.

Background: Members of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. FADS2 (fatty acid desaturase 2), also known as D6D, DES6, LLCDL2 or TU13, is a 444 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one cytochrome b5 heme-binding domain. Expressed in adult and fetal heart and in adult liver, brain, lung and retina, FADS2 functions as a component of a lipid metabolic pathway and catalyzes the first step in the pathway, namely the formation of unsaturated fatty acids from polyunsaturated fatty acids. Defects in the gene encoding FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, an affliction that is characterized by skin abnormalities, corneal ulceration and growth failure. Multiple isoforms of FADS2 exist due to alternative splicing events.