GBA Antikörper

Produktnummer ABIN1387836

Der Kaninchen Polyklonal anti-GBA Antikörper (ABIN1387836) detektiert spezifisch GBA in WB, IF, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GBA Antikörper (ABIN1387836)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GBA Antikörper

Verwendungszweck: GBA Polyclonal Antibody

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Andere Bezeichnung: GBA/Acid beta-Glucosidase

Hintergrund:

Synonyms: Glucosidase beta, Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase (alt.), Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid (includes glucosylceramidase), Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.

Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Gen-ID: 2629

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process