GBA Antikörper

Produktnummer ABIN1387836

Dieses Anti-GBA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GBA in WB, IHC (p) und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für GBA Antikörper (ABIN1387836)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GBA Antikörper

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acid beta-glucosidase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Details zu GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Andere Bezeichnung: GBA/Acid beta-Glucosidase

Hintergrund:

Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside. Defects in Beta-Glucosidase cause Gaucher disease, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system. Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases.

Synonyms: Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , GBA, Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase alt., Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid includes glucosylceramidase, Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.

Pathways: Cellular Glucan Metabolic Process