HSP70 1A/ 1B (AA 500-600) Antikörper

Produktnummer ABIN1387822

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HSP70 1A/ 1B in WB, FACS, IHC (p) und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Huhn, Maus, Schwein und Ratte. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für HSP70 1A/ 1B (AA 500-600) Antikörper (ABIN1387822)

Target: HSP70 1A/ 1B

Reaktivität: Human, Huhn, Maus, Schwein, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Produktdetails

Bindungsspezifität: AA 500-600

Kreuzreaktivität: Huhn, Human, Maus, Schwein, Ratte

Homologie: Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP70 1A/1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Oyagbemi, Omobowale, Ola-Davies, Asenuga, Ajibade, Adejumobi, Arojojoye, Afolabi, Ogunpolu, Falayi, Hassan, Ochigbo, Saba, Adedapo, Yakubu: "Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways." in: BioFactors (Oxford, England), Vol. 44, Issue 5, pp. 465-479, (2019) (PubMed).

Zheng, Liu, Li, Tang, Zhang, Tang: "Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats." in: Journal of neurosurgery, pp. 1-9, (2016) (PubMed).

Antigendetails

Target: HSP70 1A/ 1B

Andere Bezeichnung: HSP70 1A/1B

Hintergrund:

Synonyms: HSP72, HSPA1, HSP70I, HSP70-1, HSP70-1A, HEL-S-103, Heat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSX70

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

Gen-ID: 3303

UniProt: P08107