DOK5 Antikörper (AA 21-120)
Kurzübersicht für DOK5 Antikörper (AA 21-120) (ABIN1387610)
Target
Alle DOK5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 21-120
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Kreuzreaktivität
 - Human
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Homologie
 - Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic peptide derived from human DOK5/IRS6
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Isotyp
 - IgG
 
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Applikationshinweise
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                        ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
 - 12 months
 
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                                            : "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis."    in: Neuroscience letters, Vol. 553, pp. 46-51, (2013)         (PubMed).        
 
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                                            : "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis."    in: Neuroscience letters, Vol. 553, pp. 46-51, (2013)         (PubMed).        
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- DOK5 (Docking Protein 5 (DOK5))
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Andere Bezeichnung
 - DOK5
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Hintergrund
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Synonyms: IRS6, IRS-6, C2orf18, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, DOK5
Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
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Gen-ID
 - 55816
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UniProt
 - Q9P104
 
Target
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