DDX5 Antikörper (AA 301-430)

Produktnummer ABIN1387377

Dieses Anti-DDX5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DDX5 in WB und ELISA. Geeignet für Maus.

Kurzübersicht für DDX5 Antikörper (AA 301-430) (ABIN1387377)

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DDX5 Antikörper

Bindungsspezifität: AA 301-430

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDX5/p68 RNA Helicase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DDX5

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Andere Bezeichnung: DDX5

Hintergrund:

Synonyms: ATP dependent RNA helicase DDX5, DDX 5, Ddx5, DDX5_HUMAN, DEAD Asp Glu Ala Asp box helicase 5, DEAD Asp Glu Ala Asp box polypeptide 5, DEAD box 5, DEAD box protein 5, DEAD/H Asp Glu Ala Asp/His box polypeptide 5 RNA helicase, 68kD, DEAD/H Asp Glu Ala Asp/His box polypeptide 5, DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 5 RNA helicase 68 kDa, DEAD/H box-5 RNA helicase 68kD, DKFZp686J01190, G17P1, HELR, HLR 1, HLR1, HUMP68, P68, P68, p68 RNA helicase, Probable ATP dependent RNA helicase DDX5, Probable ATP-dependent RNA helicase DDX5, RNA helicase 68kD, RNA helicase p68, RNA-dependent ATPase.

Background: p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.

Gen-ID: 1655

UniProt: P17844

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus