Mycobacterium Tuberculosis Ag85 Antikörper

Produktnummer ABIN1387337

Produktdetails

Target: Mycobacterium Tuberculosis Ag85

Reaktivität: Mycobacterium tuberculosis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody will recognize Mycobacterium tuberculosis Ag85A and Ag85B

Kreuzreaktivität: Bakterien

Kreuzreaktivität (Details): Mycobacteriumtuberculosis

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Mycobacterium Tuberculosis Ag85

Andere Bezeichnung: Mycobacterium Tuberculosis Ag85B

Hintergrund:

Synonyms: Antigen 85 complex B, 30 kDa extracellular protein, Mycobacterium, Mycolyl transferase 85B, fbpB, Antigen 85-B, 85B, Ag85B, Extracellular alpha-antigen, Fibronectin-binding protein B, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Ag85A, fbpA, 85A

Background: The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.

Gen-ID: 885785, 886132

UniProt: P9WQP1, P9WQP3