NIR1 Antikörper (AA 131-250)

Produktnummer ABIN1387251

Dieses Anti-NIR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NIR1 in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für NIR1 Antikörper (AA 131-250) (ABIN1387251)

Target: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NIR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NIR1 Antikörper

Bindungsspezifität: AA 131-250

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIR1/RDGBA3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NIR1

Target: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Andere Bezeichnung: NIR1

Hintergrund:

Synonyms: membrane-associated 3, CORD5, Membrane associated phosphatidylinositol transfer protein 3, Membrane-associated phosphatidylinositol transfer protein 3, NIR 1, NIR-1, NIR1, Phosphatidylinositol transfer protein, Phosphatidylinositol transfer protein, membrane-associated 3, PITM3_HUMAN, PITPnm 3, PITPNM, PITPNM family member 3, Pitpnm3, PYK2 N terminal domain interacting receptor 1, PYK2 N-terminal domain-interacting receptor 1, RDGBA3, retinal degeneration B alpha 3.

Background: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.Involvement in disease:Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) . CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration.

Gen-ID: 83394