PAPPA2 Antikörper

Produktnummer ABIN1387223

Der Kaninchen Polyklonal Anti-PAPPA2-Antikörper wurde für WB, IF (p) und IHC (p) validiert. Er ist geeignet, PAPPA2 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für PAPPA2 Antikörper (ABIN1387223)

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPPA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PAPPA2 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAPP A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PAPPA2

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Andere Bezeichnung: PAPP A2

Hintergrund:

Synonyms: PAPPA 2, PAPP E, PAPP-A2, PAPP-E, PAPP2_HUMAN, PAPPA 2, PAPPA2, Pappalysin 2, Pappalysin-2, PLAC3, Pregnancy associated plasma protein A2, Pregnancy associated plasma protein E1, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1.

Background: Pregnancy-associated plasma protein-A (Pappalysin-1 or PAPP-A), also known as Insulin-like growth factor-dependent IGF-binding protein 4 (IGFBP4) protease, is a member of the peptidase M43B family of proteins. PAPP-A, a metalloproteinase, cleaves Insulin-like growth factor binding proteins IGFBP4 and IGFBP5, releasing bound IGF. PAPP-A is primarily expressed in septa and anchoring villi in placenta and is also expressed in pregnancy serum. Levels of PAPP-A increase throughout pregnancy. Lower levels of expression can be detected in kidney, prostate, breast, ovary and endometrial tissues. PAPP-A is a secreted protein that can form homodimers, in pregnancy serum PAPP-A may also form a heterotetramer with PRG-2.

Gen-ID: 60676