TCEANC2 Antikörper

Produktnummer ABIN1387170

Dieses Anti-TCEANC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TCEANC2 in WB, IF (p) und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für TCEANC2 Antikörper (ABIN1387170)

Target: TCEANC2 (Transcription Elongation Factor A (SII) N-Terminal and Central Domain Containing 2 (TCEANC2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEANC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TCEANC2 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf83

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TCEANC2

Target: TCEANC2 (Transcription Elongation Factor A (SII) N-Terminal and Central Domain Containing 2 (TCEANC2))

Andere Bezeichnung: C1orf83

Hintergrund:

Synonyms: chromosome 1 open reading frame 83, FLJ32112, FLJ39169, hypothetical protein LOC127428, Uncharacterized protein C1orf83, TEAN2_HUMAN.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf83 gene product has been provisionally designated C1orf83 pending further characterization. There are two isoforms of C1orf83 that are produced as a result of alternative splicing events.

Gen-ID: 127428