B4GALT7 Antikörper

Produktnummer ABIN1387134

Der Kaninchen Polyklonal anti-B4GALT7 Antikörper (ABIN1387134) detektiert spezifisch B4GALT7 in WB, IF (p) und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für B4GALT7 Antikörper (ABIN1387134)

Target: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B4GALT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-B4GALT7 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human B4GALT7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu B4GALT7

Target: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Andere Bezeichnung: B4GALT7

Hintergrund:

Synonyms: B4GAL T7, Beta 1,4 galactosyltransferase 7, Beta 1,4 GalTase 7, Beta4Gal T7, UDP Gal:beta GlcNAc beta 1,4 galactosyltransferase 7, XGALT 1, XGALT1, XGPT1, Xylosylprotein beta 1,4 galactosyltransferase, polypeptide 7, B4GT7_HUMAN.

Background: Beta-1,4-galactosyltransferases (beta-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a beta-1,4 linkage to an acceptor sugar. There are seven members of the beta-1,4-Gal-T family, all of which are directed to the golgi apparatus through a hydrophobic sequence at the N-terminus. Beta-1,4-Gal-T7, also known as B4GALT7 or XGALT1, is a 327 amino acid single-pass type II membrane protein that is expressed at high levels in heart, pancreas and liver. Beta-1,4-Gal-T7 uses manganese to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding beta-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type (EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid facies, mild mental retardation, short stature, skin hyperextensibility, moderate skin fragility, joint hypermobility principally in digits. Beta-1,4-galactosyltransferases (Beta-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a beta-1,4 linkage to an acceptor sugar.

Gen-ID: 11285

Pathways: Glycosaminoglycan Metabolic Process