PDE4A Antikörper

Produktnummer ABIN1387127

Produktdetails anti-PDE4A Antikörper

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDE4A8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PDE4A

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Abstract: PDE4A Produkte

Synonyme: pde4 antikoerper, dpde2 antikoerper, pde46 antikoerper, PDE4A antikoerper, Pde4a antikoerper, D9Ertd60e antikoerper, Dpde2 antikoerper, DPDE2 antikoerper, PDE4 antikoerper, PDE46 antikoerper, PHOSA antikoerper, phosphodiesterase 4A S homeolog antikoerper, phosphodiesterase 4A, cAMP-specific antikoerper, phosphodiesterase 4A antikoerper, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) antikoerper, cAMP-specific 3',5'-cyclic phosphodiesterase 4A antikoerper, phosphodiesterase 4A, cAMP specific antikoerper, phosphodiesterase 4C antikoerper, pde4a.S antikoerper, pde4a antikoerper, PDE4A antikoerper, LOC100009247 antikoerper, Pde4a antikoerper, PDE4C antikoerper

Hintergrund:

Synonyms: 2EL, DPDE2, PDE4, PDE46, PDE4A, Phosphodiesterase 4A, Phosphodiesterse Type 4A8, PDE4A_HUMAN.

Background: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

Gen-ID: 5141

Pathways: cAMP Metabolic Process