Kininogen-1 Light Chain Antikörper

Produktnummer ABIN1387091

Der Kaninchen Polyklonal anti-Kininogen-1 Light Chain Antikörper wird verwendet zum Nachweis von Kininogen-1 Light Chain in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF (p) und IHC (p).

Kurzübersicht für Kininogen-1 Light Chain Antikörper (ABIN1387091)

Target: Kininogen-1 Light Chain

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMW Kininogen-1 light chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Kininogen-1 Light Chain

Hintergrund:

Synonyms: Alpha 2 thiol proteinase inhibitor, HMW Kininogen light Chain, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Ile-Ser-Bradykinin, Kallidin I, Kallidin II, Kininogen 1, KNG1, KNG1_HUMAN, Low molecular weight growth-promoting factor, Williams-Fitzgerald-Flaujeac factor.

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

Gen-ID: 3827