ODF3 Antikörper

Produktnummer ABIN1387063

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ODF3 in WB, IHC (p) und IF (p). Er zeigt eine Reaktivität gegenüber Maus, Human und Ratte.

Kurzübersicht für ODF3 Antikörper (ABIN1387063)

Target: ODF3 (Outer Dense Fiber of Sperm Tails 3 (ODF3))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ODF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ODF3 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODF3/CT135

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ODF3

Target: ODF3 (Outer Dense Fiber of Sperm Tails 3 (ODF3))

Andere Bezeichnung: CT135

Hintergrund:

Synonyms: Cancer/testis antigen 135, CT135, hSHIPPO, odf3, ODF3A_HUMAN, Outer dense fiber of sperm tails 3, Outer dense fiber of sperm tails protein 3, Outer dense fiber protein 3, SHIPPO1, Sperm tail protein SHIPPO 1, Sperm tail protein SHIPPO1, TISP50, Transcript induced in spermiogenesis protein 50.

Background: Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.Constituting the main cytoskeletal structure of spermatid flagella, outer dense fibers (ODFs) add elastic recoil, stiffness and protection against shear forces during sperm movement. Human ODFs consist of approximately 10 major and at least 15 minor proteins. The major proteins of the ODF include Odf1, Odf2, and Odf3, which compose a family of proteins that are preferentially expressed during mammalian spermiogenesis. Odf3 (outer dense fiber protein 3), also known as sperm tail protein SHIPPO 1 and TISP50 (transcript induced in spermiogenesis protein 50), is a 254 amino acid protein that is expressed during the latter part of spermatogenesis in flagella of elongated spermatids and mature sperm. Odf proteins are directed to their exact subcellular location by Spags, which are characterized as chaperone-like Odf-binding molecules. There are two isoforms of Odf3 that are produced as a result of alternative splicing events.

Gen-ID: 113746