STIL Antikörper

Produktnummer ABIN1387013

Der Kaninchen Polyklonal Anti-STIL-Antikörper wurde für WB, IF (p) und IHC (p) validiert. Er ist geeignet, STIL in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für STIL Antikörper (ABIN1387013)

Target: STIL (SCL/TAL1 Interrupting Locus (STIL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-STIL Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STIL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu STIL

Target: STIL (SCL/TAL1 Interrupting Locus (STIL))

Andere Bezeichnung: STIL

Hintergrund:

Synonyms: MCPH7, SCL interrupting locus protein, SCL-interrupting locus protein, SCL/TAL1 interrupting locus, SIL, STIL, STIL_HUMAN, TAL 1 interrupting locus protein, TAL-1-interrupting locus protein.

Background: TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.

Gen-ID: 6491

Pathways: Tube Formation