SLFN14 Antikörper

Produktnummer ABIN1386973

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLFN14 in WB, IF (p) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SLFN14 Antikörper (ABIN1386973)

Target: SLFN14 (Schlafen Family Member 14 (SLFN14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLFN14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SLFN14 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLFN14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SLFN14

Target: SLFN14 (Schlafen Family Member 14 (SLFN14))

Andere Bezeichnung: SLFN14

Hintergrund:

Synonyms: Schlafen family member 14, SLFN14, SLN14_HUMAN.

Background: Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

Gen-ID: 342618

UniProt: P0C7P3