ANKS6 Antikörper

Produktnummer ABIN1386931

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ANKS6 in WB, IF (p) und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ANKS6 Antikörper (ABIN1386931)

Target: ANKS6 (Ankyrin Repeat and Sterile alpha Motif Domain Containing 6 (ANKS6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ANKS6 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKS6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ANKS6

Target: ANKS6 (Ankyrin Repeat and Sterile alpha Motif Domain Containing 6 (ANKS6))

Andere Bezeichnung: ANKS6

Hintergrund:

Synonyms: ANKRD14, Anks6, ANKS6_HUMAN, ankyrin repeat and SAM domain containing protein 6, Ankyrin repeat and SAM domain-containing protein 6, ankyrin repeat domain 14, ankyrin repeat domain containing protein 14, Ankyrin repeat domain-containing protein 14, SAM domain containing protein 6, SAM domain-containing protein 6, SamCystin, SAMD6, sterile alpha mot domain containing 6, sterile alpha mot domain containing protein 6, Sterile alpha mot domain-containing protein 6.

Background: ANKS6, also known as ankyrin repeat domain-containing protein 14, SAMD6 (sterile alpha motif domain-containing protein 6), SamCystin or PKDR1, is an 871 amino acid phosphoprotein that contains eleven ANK repeats, one SAM domain and exists as three alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 9q22.33, ANKS6 is necessary for renal function and is linked to renal cyst formation in polycystic kidney disease. ANKS6 interacts with BICC1, another protein linked to polycystic kidney disease, and both co-localize to the same cell region. ANKS6 is involved in proteinprotein interactions with both itself as well as BICC1, and both proteins function in a molecular pathway that is linked to cystogenesis. ANKS6 may also be associated with dental anomolies.

Gen-ID: 203286