TENM3 Antikörper

Produktnummer ABIN1386911

Der Kaninchen Polyklonal Anti-TENM3-Antikörper wurde für IF (p) und IHC (p) validiert. Er ist geeignet, TENM3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TENM3 Antikörper (ABIN1386911)

Target: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TENM3 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TENM3 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ODZ3/Teneurin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TENM3

Target: TENM3 (ODZ3) (Teneurin 3 (ODZ3))

Andere Bezeichnung: ODZ3

Hintergrund:

Synonyms: ODZ3 like protein, Protein Odd Oz ten m homolog 3, Ten 3, Ten M3, Tenascin M3, Teneurin 3, Teneurin3, TNM3, FLJ10474, FLJ10886, KIAA1455, odd Oz Ten m homolog 3, odz odd Oz ten m homolog 3 Drosophila, odz odd Oz ten m homolog 3, TEN3_HUMAN.

Background: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localized to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.