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IQCC Antikörper

This anti-IQCC antibody (ABIN1386889) is a Rabbit Polyclonal antibody detecting IQCC in WB, IF (p), IHC (p). Suitable for Human, Mouse, Rat.
Produktnummer ABIN1386889

Quick Overview for IQCC Antikörper (ABIN1386889)

Target

IQCC (IQ Motif Containing C (IQCC))

Reaktivität

Human, Maus, Ratte

Wirt

  • 12
Kaninchen

Klonalität

  • 11
Polyklonal

Konjugat

  • 8
  • 2
  • 1
  • 1
Dieser IQCC Antikörper ist unkonjugiert

Applikation

  • 6
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IQCC

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IQCC (IQ Motif Containing C (IQCC))

    Andere Bezeichnung

    IQCC

    Hintergrund

    Synonyms: IQ domain containing protein C, IQ domain-containing protein C, IQ mot containing C, Iqcc, IQCC_HUMAN.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

    Gen-ID

    55721
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