RAB40A Antikörper (AA 171-277)

Produktnummer ABIN1386817

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAB40A in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RAB40A Antikörper (AA 171-277) (ABIN1386817)

Target: RAB40A (RAB40A, Member RAS Oncogene Family (RAB40A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB40A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RAB40A Antikörper

Bindungsspezifität: AA 171-277

Homologie: Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAB40A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RAB40A

Target: RAB40A (RAB40A, Member RAS Oncogene Family (RAB40A))

Andere Bezeichnung: RAB40A

Hintergrund:

Synonyms: Protein Rar 2, RAB40A, member RAS oncogene family, Rar 2, RAR2A, Ras related protein Rab 40A, SOCS box containing protein RAR2A, RB40A_HUMAN.

Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 40A, Rab 40B and Rab 40C each contain one SOCS box domain and are members of the Rab subfamily of GTPases. Localized to the cytoplasmic side of the cell membrane, Rab 40A, Rab 40B and Rab 40C are thought to function as substrate-recognition components of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that functions to mediate the degradation of target proteins.

Gen-ID: 142684